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Comment on New DNA construct can set off a “mutagenic chain reaction”

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Well, I guess we'll start seeing the importance of backups. Get a set made at birth, along with whatever fetal/cord-blood stem cell reserves the individual could use later...

To clarify with respect to the linked article and technique, this is about a genetically modified individual passing on the modification to their children. There's no 'chain reaction' through existing fully grown cells and they can't propagate a modification through your cells (yet, at least!).

That was not at all clear from the article. So the (fruit fly) intervention happens one cell at a time? And only if by luck it's a gamete that is affected?

True, but if you have archives going further back than the change, you can at least figure out what it displaced.

I'd expect every child having their genome sequenced at birth (if not earlier), within a decade.

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