use baculovirus to serially and temporally express telomerase and keep the telomere count between 3000-8000 for all cells in the human body. Then figure out some way to flush out senescent cells
Apparently there's some work happening now with mice, to activate a gene that selectively eliminates senescent cells ( from Google ) - but gene manipulation after birth is unfeasible, isn't it? What other ways could there be?
RE: Baculovirus, have you seen any attempts at this?
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use baculovirus to serially and temporally express telomerase and keep the telomere count between 3000-8000 for all cells in the human body. Then figure out some way to flush out senescent cells
Apparently there's some work happening now with mice, to activate a gene that selectively eliminates senescent cells ( from Google ) - but gene manipulation after birth is unfeasible, isn't it? What other ways could there be?
RE: Baculovirus, have you seen any attempts at this?
Yes, plenty of labs use this regularly on mammalian cells and mice etc. Nobody has used it clinically though ...