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Comment on Diary of an Insane Cell Mechanic (2003)

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My god. it's like he did my rotation in a wet lab. Very similar set of experiences.

BTW: Maniatis as a lab manual set back molecular biology by years! Almost every protocol in the book was wrong, missing some technical component. It's as if "Intro To Python" left out important code statements and just kind of let you figure it out from first principles.

Is there a new canonical lab manual ?

I don't know. It's possible the manual was updated/improved. Also, service labs got really cheap, cheaper than grad students.

is it easier these days (since ~2000) to outsource lab work to other countries ? i would imagine shipping + people in china / india are much cheaper than even grad students.

Sure, this is common.

You can also outsource it within your own country (I'm assuming US here, but Europe also qualifies).

The Atul Butte lab at Stanford uses this: https://www.assaydepot.com/

One of the interesting areas is "third-party multiservice". instead of acting as an exchange depot (send request to first service, get results back, ship resuls to second service, etc), the idea is to file an order with the first service, and chain the shipping to the next company, etc, so that only the finished product makes it back to the requestor.

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