What i'd like to see, and as far as i know it doesn't exist in any browser, is a way to prevent any extensions from running on certain sites. I want some things like adblock installed for general browsing, but there's no reason i need it running on my email, my banking, my employer's control panel. I can white-list sites inside of extensions, but that still leaves me trusting the extension to properly implement their white-listing feature. I'd much rather have chrome managing a list of sites where the extension doesn't get to run at all.