It's not the start ups, but the investing circles that make the hub. Start ups can move pretty freely, but angels and VC's appear to be more set in one location. If you can convince gutsy angels to move from San Fran to Boston, or get Boston angels to be more bold with their investments, then Boston has a chance. Otherwise, it's not worth it for innovative start ups to stay in Boston.
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It's not the start ups, but the investing circles that make the hub. Start ups can move pretty freely, but angels and VC's appear to be more set in one location. If you can convince gutsy angels to move from San Fran to Boston, or get Boston angels to be more bold with their investments, then Boston has a chance. Otherwise, it's not worth it for innovative start ups to stay in Boston.