Transpiled asm.js code beats the pants off non-asm.js code in almost every regard. Period. I have not seen a single case where code heavily leveraging the JS GC heap, etc. will outperform the typed array, virtual heap, etc. style even WITHOUT the benefit of asm.js's AOT compilation.

It's possible, of course, but I've never seen it. And I certainly haven't found any way to achieve it with a compiler. If you have, let me know...