Its not really a question of what you'd prefer to code in (you'll always prefer something familiar) but what delivers the best result for what you're trying to do. In essence we created two real, not test, apps, one using HTML and one using Objective-C. The clear winner was Objective-C in our experience, at this time. Creating a great mobile interface using HTML5 is certainly worth doing and can be done - but I dont think it should be made to look and feel like an app (either in safari or wrapped) since the "not-quite-right" issues just keep piling up, and if you want the look and feel of iOS you should just go native in the first place.
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Its not really a question of what you'd prefer to code in (you'll always prefer something familiar) but what delivers the best result for what you're trying to do. In essence we created two real, not test, apps, one using HTML and one using Objective-C. The clear winner was Objective-C in our experience, at this time. Creating a great mobile interface using HTML5 is certainly worth doing and can be done - but I dont think it should be made to look and feel like an app (either in safari or wrapped) since the "not-quite-right" issues just keep piling up, and if you want the look and feel of iOS you should just go native in the first place.