But "the generated types will be isomorphic but incompatible" is right. It is ok if you have lib_a.c and lib_b.c because these are two separate translation units. But this only works if both of these libraries use the list type internally and pass the pointer to each other as a void pointer. The moment you have two headers lib_a.h lib_b.h both including header_only_list.h and defining an API using a generic type list(int) and where you then try to also include lib_b.h from lib_a.c it does not work.