While AlphaFold is great, to my knowledge, these proteins have several non-significant IDRs (intrinsically disordered regions), which have been and continue to be hard to model with AlphaFold. I work on computational modeling, so if I had to guess, I'm very unsure if people are using it for whole protein modeling, rather than looking at more specific domains where it probably does much better.
Comments
While AlphaFold is great, to my knowledge, these proteins have several non-significant IDRs (intrinsically disordered regions), which have been and continue to be hard to model with AlphaFold. I work on computational modeling, so if I had to guess, I'm very unsure if people are using it for whole protein modeling, rather than looking at more specific domains where it probably does much better.