High bicarbonate in blood is not a blood disease, in the same way that high glucose in blood is not a blood disease either. High bicarbonate leads to severe and serious problems that can be fatal in those with weak lungs or a weak heart and in children and the elderly. Even in healthy persons, high bicarbonate will lead to low extracellular potassium which is immediately detrimental to the heart. I have experienced it first hand. There is a reason why bicarbonate in blood has a reference range.