In the movie The Thirteenth Floor, the main character breaks out of his simulation (which also contained a simulation) into 'the real world', which changes almost exactly nothing about the presence or otherwise of an afterlife because the simulation was a simulation of the real world; the rules are the same. The boundaries of that real world are also applicable to all recursive simulations.

But this isn’t true - if universe A simulates universe B, there is no requirement that they have the same laws of physics.

If we are living in a computer simulation, then the “real” laws of physics might be radically different from the apparent ones, and we might never know what the “real” laws are