in my 40s here as well, career shift is not a an odd thing anymore these days (i guess), myself (Elementary Teacher for 2 years with university degree > Civil engineer for 7 years with univ degree > software engineer without a degree 3 years indie sole projects > now considering career shift again but still not sure to what!)

I think its up to your goals (you go after what drives you ) if its moeny then go wherever money-industries go, if its passion then go be creative and let the passion drives you.

Best of luck whatever you choose