I'm using the RequestPolicy addon for Firefox (I realize I'm in a tiny minority...). When visitng a website that uses domain sharding for the first time, that means I have to allow cross-site requests to the other domains.

My plea to web-admins: Try to at least make the names of the shards recognizable. I've seen sites where the domain is essentialy "mynewspaper.com" and it needs data from "xac1h139a.com" to display correctly. Now go find the right domain to allow within the dozens of cross site requests that such sites are often using...

Edit: This is a comment on his suggestion to use domain sharding. His site is fine.