One advantage I've noticed for Tailwind:

- If you just paste an outerHTML from the dev tools, AI coding agents can immediately figure out what it will look like; debug styles; etc.

I personally preferred PicoCSS for a long time. Pico was nice, but it injected a lot of CSS var noise into the dev tools and I started fighting with the breakpoints.

More recently, I've been just doing handcrafted CSS with a bit of OpenProps.