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Comment on Psilocybin triggers activity-dependent rewiring of large-scale cortical networks

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Mice are going to have the best mental health in the Universe before the decade is out.

I wouldn't apply the usual "but mice" appeal to purity in this case.

For one, the paper specifically studied brain structures that are directly homologous in both mice and humans (retrosplenial cortex). The researchers specifically targeted evolutionarily-conserved circuitry.

Second, there is already human research on the topic, too, and this paper is reporting on a likely mechanism to understand "why" rather than "if." Here's one from a Yale researcher:

https://news.yale.edu/2025/09/23/psilocybin-breakthrough-men...

Thanks for the chuckle

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