Comment on Diff AlgorithmsparentComments−npsomaratna11moOut of curiosity, are there any algorithms faster than BLAST? (For DNA search).−dekhn11moFor DNA? Not sure. https://pmc.ncbi.nlm.nih.gov/articles/PMC3197634/ claims it's reached parity on protein sequences.I'd much rather have a slower, but more accurate searcher, or one that was easier to use as an API.−shakow11moThere have been countless specializations and improvements on the original BLAST (which itself evolved).When I left the field, the latest hottest thing was diamond (https://github.com/bbuchfink/diamond).
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Out of curiosity, are there any algorithms faster than BLAST? (For DNA search).
For DNA? Not sure. https://pmc.ncbi.nlm.nih.gov/articles/PMC3197634/ claims it's reached parity on protein sequences.
I'd much rather have a slower, but more accurate searcher, or one that was easier to use as an API.
There have been countless specializations and improvements on the original BLAST (which itself evolved).
When I left the field, the latest hottest thing was diamond (https://github.com/bbuchfink/diamond).