AI Alignment is different because it is trying to align something which is completely human made.

Not sure what you’re getting at here; pharmaceuticals are also human made. The point in the blog post was that we should also want drugs (for example) to be aligned to our values.

What I think is absolutely important to understand is that throughout human history "alignment" has never happened.

Agree with that. This is a journey, not a destination. It’s a practice, not a mathematical problem to be solved. With no end in sight. In the same way that “perfect ethics” will never be achieved.