IIRC folate also share this property. It helps where tissues have fast growth or replenishment rates (infants still developing in utero, lifelong hair growth, digestive system lining, skin, et cetera), but as a side effect, when cancer happens, it supercharges tumors. Situations like this are probably one contributor for life extension being a difficult problem. When you try to apply a given fix you end increasing the risk of something else in the body breaking.