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Are you not familiar with any of the research linking high CO2 with harmed cognition and harmed alertness? It is manifest at as low as 800 ppm, certainly at 1000 ppm, and personally even at 600 ppm for me. There is good reason to want the preindustrial level that humans lived with for almost their entire history.

Yes, I've seen such research, but I am highly skeptical, to put it very mildly. This actually being the case is simply implausible from the physiological perspective, considering the very high (and constantly changing) concentration of CO2 in the lungs and in the bloodstream. Early research with Navy submariners was consistent with this -- no detectable impairment below 1% (10,000 ppm) and clear impairment at 3-4%. Later long term studies with 0.5% exposure (5,000 ppm) also found nothing. I put the recently popular research showing cognitive impairment as low as 600 ppm in the same mental niche as vitamin megadosing -- underpowered, low quality research with no basis in human physiology.

That said, CO2 can often serve as an easily measurable proxy for stuffy air, which can contain particulates, formaldehyde and other organic exhalations which may actually have some effect (psychological, if nothing else). But this just calls for ventilation and air filtering, not CO2 scrubbing.

It is me who is skeptical of extremely healthy test subjects in their early 20s being used to define what's healthy for the population at large. As for vitamin dosing, there is most certainly an optimal dose and form of each vitamin, somewhere between its lower and upper limits.

Offices have high ventilation but also high CO2, and the effect shows clearly in a meeting room, putting people to sleep.

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