It's really unfortunate that this would be so hard to use in production due to lack of a suitable IE fallback. If a browser doesn't support @font-face, for example, you can always fall back to a standard font. For isometric text though, lack of support would likely disrupt the page layout so badly that the only fallback solution would be images.

That said, as easy as it is to think of sites where isometric text would be a cool design element, I can't easily think of an application where it would need to be actual, editable text. Perhaps if you had a heavily futuristic themed CMS site...