I switched from a Kinesis Advantage 2 to a Glove80 over 1.5 years ago (not custom, I know) and I love it.

I also made some Dactyl Manuforms, but their key wells are not as nice as the Advantage, let alone the Glove80. They also have pretty bad thumb clusters (though with Cosmos it's configurable), not a good palm rest, etc. The only custom board I would be interested in (if the Glove didn't happen) would be:

https://github.com/wizarddata/Ergo-S-1

Since it also seems to have good palm rests, etc.