At the end of the day there is no permanent solution.

In nature we typically don't see something 'win' and that's the end of the story. I mean yes things do go extinct, but the winner always has something new to deal with. Could be a more advanced predator eating all it's food sources. Could be a bacteria that it's not resistant to. Simply put, when there's entropy on the table, something is going to evolve to take it with the least amount of work possible.