Sam Bankman-Fried Confirmed He Wears an Emsam Patch. [...] The Emsam patch contains something called Selegiline, which was originally used primarily to treat Parkinson's.
MAO-B and A inhibitors (they inhibit the enzymes that break down dopamine, serotonin and other amines) are not too uncommon to be used as nootropics in the nootropic communities, and selegiline has probably some more nootropic effects. It is also used for ADHD. While definitely indication of risky behaviour (disrupting body's homeostatic and allostatic mechanisms is quite risky, people can die when taking this together with foods high in tyrosine) I doubt he used it specifically to increase impulsivity.
That doesn't sound smart at all. There are many safer ways of acting on the dopamine pathway(s) than directly going for L-dopa (which, unlike a lot of other substances, isn't rate limited by subsequent bioprocesses).
Comments
SBF did it intentionally (so he says).
https://slate.com/technology/2022/12/sam-bankman-fried-ftx-e...
MAO-B and A inhibitors (they inhibit the enzymes that break down dopamine, serotonin and other amines) are not too uncommon to be used as nootropics in the nootropic communities, and selegiline has probably some more nootropic effects. It is also used for ADHD. While definitely indication of risky behaviour (disrupting body's homeostatic and allostatic mechanisms is quite risky, people can die when taking this together with foods high in tyrosine) I doubt he used it specifically to increase impulsivity.
That doesn't sound smart at all. There are many safer ways of acting on the dopamine pathway(s) than directly going for L-dopa (which, unlike a lot of other substances, isn't rate limited by subsequent bioprocesses).
SBF is kinda known for doing things that don’t sound smart at all