Fair enough, FWIW I wasn't trying to take it out of context. It seemed to me like a separate thread of thought being in the parens, but that's purely interpretive on my part. IMHO it would have been more clear to me your intention if you had said "(opioids are terrible for that)" or something similar. But that said I'm much too sensitive about the attacks on opiods because it's very much in the zeitgeist right now, and that would make me prone to defensiveness.