I mean not exactly... It depends on the type of simulation we could be in. If we're in the type that is monitored and if we could find a way to mess with the simulation that we'd just be rolled back to a previous state, then yes, it's impossible. If instead it's watched about as well as some of us monitor our own VMs, well, maybe a different story. Of course we're still a long way from many things in physics like a theory of everything, so no need to worry about being in a simulation at this time.