I gave Venture Bros a look a while back, and it scratched my pop-culture references + nihilism itch way better than Rick and Morty ever did. I don't know why though.

Nothing matters in Rick and Morty because they can always hop to another universe (as that universe's Rick and Morty die) and pick up where they left off. Similarly, Venture Bros nothing matters cause everyone can be cloned and fixed even if they die.

But somehow, Venture Bros hits my funny bone way harder.