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@JamesianP - You're exactly right about the heady requirement lift. And there are plenty of widely-defined computational chemistry jobs, especially when you throw in the bio- prefix.

As for the adjacent niche bit, right again as you are about experience. My time as a so-called "data scientist" was never really the best fit, and I could never compete with the folks who do Kaggle competitions and have a real passion for AI/ML (which, to me, is one of the defining points of "data science" today).

However, I've logged a lot of time over the past 30+ years in front of the terminal, so fingers crossed!

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