You can especially see this at your local Goodwill (in the US) - all the hardcover books are of a certain "bestseller" type and many will be clearly never even opened.
Meanwhile actual second-hand bookstores often specialize in something (there was a really good one that specialized in science fiction) - they still have a normal selection of books like a small library, but most of the shelf space is whatever they specialize in.
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You can especially see this at your local Goodwill (in the US) - all the hardcover books are of a certain "bestseller" type and many will be clearly never even opened.
Meanwhile actual second-hand bookstores often specialize in something (there was a really good one that specialized in science fiction) - they still have a normal selection of books like a small library, but most of the shelf space is whatever they specialize in.