> 23andMe’s paper includes a new estimate that the heritability of Parkinson’s Disease is 23% (suggesting that 77% of the variance will never be explained by genes, but that missing genes yet to be discovered account for a further 16%).
That's not correct. There is more to heritability than just genes, so it is not at all guaranteed that the extra 16% can be accounted for by sequencing the rest of the genome.
Also, the headline is rather sensationalist as none of this is particularly surprising. GWAS studies have produced underwhelming results for many years.
Comments
> 23andMe’s paper includes a new estimate that the heritability of Parkinson’s Disease is 23% (suggesting that 77% of the variance will never be explained by genes, but that missing genes yet to be discovered account for a further 16%).
That's not correct. There is more to heritability than just genes, so it is not at all guaranteed that the extra 16% can be accounted for by sequencing the rest of the genome.
Also, the headline is rather sensationalist as none of this is particularly surprising. GWAS studies have produced underwhelming results for many years.