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I imagine that would make it harder to compare against how it could potentially work for humans. Humans have many medications that they can take to fix side effects that might arise from this, including side effects that can result in death or lower quality of life. Like, inflammation can be fixed with anti-inflammation medication. Not a biologist, but probably you’re expecting too much from mice trials because it seems very much like early drug discoveries compared to human trials.

He’s saying treatment so someone lives another week is qualitatively different from treatment so someone lives long enough to die of something else.

Yes, I get that. But actually designing experiments that measures the latter case using mice is extremely difficult and probably impossible. Especially because you are designing these experiments in order to see how these cures might work on humans.

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