Combination of Wellbutrin & Dextromethorphan -- which is a dissociative with some side-effects similar to Ketamine. It's in trial for severe depression treatment. 15mg of DXM (which you can buy at any drug store) combined with 150mg Wellbutrin (which you can get your dr. to prescribe to you.) Could be worth a try...
I'm actually on wellbutrin, double that dose though, and have done dxm a few times. It's... Different. Very similar in dissociation, but ketamine dissociation for me I can actually go in with planned introspection in mind while I lose all sense of self and become one with whatever music I'm listening to, but dxm just makes me 'out of it', if that makes any sense.
Certainly, I'm well aware of DXM's side-effects (at 'recreational' doses). The point of the trial is to use very low doses of it though, on a regular basis.
It's funny though, if I were to compare recreational DXM to Ketamine I would describe them exactly opposite as you did.
15mg of DXM (which you can buy at any drug store) combined with 150mg Wellbutrin (which you can get your dr. to prescribe to you.) Could be worth a try...
Out of curiosity, where did you get these dosage numbers from?
The linked wiki page doesn't mention dosage and the source on wikipedia is paywalled.
Comments
Last time this topic came up on HN this came up: https://en.wikipedia.org/wiki/Bupropion/dextromethorphan
Combination of Wellbutrin & Dextromethorphan -- which is a dissociative with some side-effects similar to Ketamine. It's in trial for severe depression treatment. 15mg of DXM (which you can buy at any drug store) combined with 150mg Wellbutrin (which you can get your dr. to prescribe to you.) Could be worth a try...
I'm actually on wellbutrin, double that dose though, and have done dxm a few times. It's... Different. Very similar in dissociation, but ketamine dissociation for me I can actually go in with planned introspection in mind while I lose all sense of self and become one with whatever music I'm listening to, but dxm just makes me 'out of it', if that makes any sense.
Certainly, I'm well aware of DXM's side-effects (at 'recreational' doses). The point of the trial is to use very low doses of it though, on a regular basis.
It's funny though, if I were to compare recreational DXM to Ketamine I would describe them exactly opposite as you did.
Out of curiosity, where did you get these dosage numbers from?
The linked wiki page doesn't mention dosage and the source on wikipedia is paywalled.
I'm trying to find where I read this last time this came up on HN. In the meantime, this presentation goes into more detail on the psychopharmacology: http://media.corporate-ir.net/media_files/IROL/25/254022/Psy...
EDIT: looks like it's 60mg of DM, which seems rather high.