The Native American Church (NAC), also known as Peyotism and Peyote Religion, is a Native American religion that teaches a combination of traditional Native American beliefs and Christianity, with sacramental use of the entheogen peyote.[1] The religion originated in the Oklahoma Territory (1890-1907) in the late nineteenth century, after peyote was introduced to the southern Great Plains from Mexico.[1][2][3] Today it is the most widespread indigenous religion among Native Americans in the United States (except Alaska Natives and Native Hawaiians), Canada (specifically First Nations people in Saskatchewan and Alberta), and Mexico, with an estimated 250,000 adherents as of the late twentieth century.

https://en.wikipedia.org/wiki/Native_American_Church