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Comment on Nicotinamide riboside effects on aging similar to caloric restrictionparent

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Compliance for CR is near impossible though. I'm a believer in it but am still 10 pounds overweight. It won't work for everyone, obviously (because so many of us are overweight).

It's not impossible. Look at the CR experiments like CALERIE. Dropout is something like 10-20%, similar to intermittent fasting or other kinds of diets.

I'd heard CALORIE was selective with applicants in order to increase compliance.

Most studies are.

Intermittent fasting is not that hard.

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