Reading through the paper it seems like all the statistics are presented as Odds Raios vs placebo. But I couldn't find the actual efficacy of placebo. Did I miss it or does someone know?
Something being twice as effective as a placebo is great when the placebo effect helps 30% of patients, not so much when it's 3%
placebo rates would be something in the 15-40% remission rate range, in small RCTs. it varies more than you would think from one trial to another. antidepressant efficacy would be something like 20-45%. recovery rates are usually higher in smaller trials, and lower in bigger trials, partly because people get more high-touch service in smaller academic studies
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Reading through the paper it seems like all the statistics are presented as Odds Raios vs placebo. But I couldn't find the actual efficacy of placebo. Did I miss it or does someone know?
Something being twice as effective as a placebo is great when the placebo effect helps 30% of patients, not so much when it's 3%
placebo rates would be something in the 15-40% remission rate range, in small RCTs. it varies more than you would think from one trial to another. antidepressant efficacy would be something like 20-45%. recovery rates are usually higher in smaller trials, and lower in bigger trials, partly because people get more high-touch service in smaller academic studies