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Answering this question will require multiple pages so I will just stay with the work I am doing: gene therapy. Some new strategies seem to be relatively successful. For instance my group has developed a way to target the healthy surrounding area of the tumor to start "attacking" the tumor. Read this if you're interested in this: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863297/?tool=pu...

As for the challenges the blood-brain barrier makes reaching the brain difficult. And even when we reach the brain its size makes it hard penetrate it deeply. However new research is coming out every month that one by one solve these obstacles. There is a long road ahead though.

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