"Random is blotchy". At 1 out of 100, you don't have to know that many people who are able to get Parkinson's to have a non-trivial chance of seeing "more than expected" the number of cases. I don't know anybody with Parkinson's, and I "should", I know well more than 100 people who could have it, and if they did, I would know. And of all the people reading these comments and able to post, the odds that at least one would be in a "comment-worthy" blotch is basically 100%.
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"Random is blotchy". At 1 out of 100, you don't have to know that many people who are able to get Parkinson's to have a non-trivial chance of seeing "more than expected" the number of cases. I don't know anybody with Parkinson's, and I "should", I know well more than 100 people who could have it, and if they did, I would know. And of all the people reading these comments and able to post, the odds that at least one would be in a "comment-worthy" blotch is basically 100%.