I would say it could still be susceptible to malware since a lot of it gets installed on account of user stupidity, but anything that requires exploitation of a specific memory address will fail. Of course though, I think the latest version of Windows has protection against that as well by making it difficult or impossible to determine what addresses will be used when a program is ran. (Maybe, my memory of that is admittedly fuzzy.)
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Why wouldn't it be susceptible to malware? The fact that that question is even worth asking demonstrates that you've abused the phrase "by definition"
I would say it could still be susceptible to malware since a lot of it gets installed on account of user stupidity, but anything that requires exploitation of a specific memory address will fail. Of course though, I think the latest version of Windows has protection against that as well by making it difficult or impossible to determine what addresses will be used when a program is ran. (Maybe, my memory of that is admittedly fuzzy.)