In Bitcoin, these final nodes are called UTXOs (unspent transaction outputs), and indeed if you use chain pruning or a light client, they are all you need. They also need to be searched quickly to verify transactions, so they are usually kept in RAM. Because they cannot be pruned, there is a soft fork being developed called SegWit that changes the accounting so that transactions cost more if they create many unspent outputs, or cost less if they spend more outputs than they create.