So, my 2 cents: First, sign up with as many ad networks as you can. Then, note the CPMs that you are getting with each ad network. Finally, chain the ad tags together using minimums and redirects. For example, say you've tried 5 ad networks: A, B, C, D, and AdSense. Put ad tags from A on your site, and redirect to B if A goes below a certain minimum. Then redirect to C if B goes below another lower minimum. Keep redirecting until you get to AdSense, the internet's remnant provider.
Every once in a while, check in and make sure that your redirects and minimums are making sense. If you do this, then you'll be capturing a pretty high CPM. To my knowledge, almost all networks support this structure, except for AdSense, which doesn't redirect and therefor goes at the end of the chain.
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When is a good time to switch, and where to? Does it make sense for smaller sites, too?
So, my 2 cents: First, sign up with as many ad networks as you can. Then, note the CPMs that you are getting with each ad network. Finally, chain the ad tags together using minimums and redirects. For example, say you've tried 5 ad networks: A, B, C, D, and AdSense. Put ad tags from A on your site, and redirect to B if A goes below a certain minimum. Then redirect to C if B goes below another lower minimum. Keep redirecting until you get to AdSense, the internet's remnant provider.
Every once in a while, check in and make sure that your redirects and minimums are making sense. If you do this, then you'll be capturing a pretty high CPM. To my knowledge, almost all networks support this structure, except for AdSense, which doesn't redirect and therefor goes at the end of the chain.