I split 75/25% client/server (Python/Pylons/Django) and find the server stuff easier. The thing about doing server development is that once it's working, it's working. On the client side, once you get it working you're only halfway there unless you're doing boring stuff.
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What about JS server-side programming? ;)
I imagine if you were a front-end JS programmer by day but doing your fair share of Python / Django then the JS would be a bit easier.
I split 75/25% client/server (Python/Pylons/Django) and find the server stuff easier. The thing about doing server development is that once it's working, it's working. On the client side, once you get it working you're only halfway there unless you're doing boring stuff.
I'm a back-end programmer by day who dreams of doing embedded work. Hacking the DOM in js is not my specialty.
That said, I've hacked around with node.js.