At that point I would imagine it's the same concept as net carbs. Obviously not all food/matter is digestible. I do think it's still safe to say calories in/calories out however since most of us aren't entering shredded paper, charcoal and wood into MFP logs.
While you can control the input, the output gets harder - one cannot just simply double/triple their defecation rate, and exercise tends to work out an appetite.
Output is governed by hormones, and the only reliable hack for now seems to be significantly lowering insulin by switching to ketogenic diet (or a variation thereof, /r/zerocarb, /r/keto, Atkins, Dukan). I'd recommend this book https://en.wikipedia.org/wiki/Good_Calories,_Bad_Calories with understanding that a lot of nutrition and diet science is in very premature stage because of World War 2 and lack of funding thereafter.
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At that point I would imagine it's the same concept as net carbs. Obviously not all food/matter is digestible. I do think it's still safe to say calories in/calories out however since most of us aren't entering shredded paper, charcoal and wood into MFP logs.
While you can control the input, the output gets harder - one cannot just simply double/triple their defecation rate, and exercise tends to work out an appetite.
http://well.blogs.nytimes.com/2014/11/12/exercising-but-gain...
Output is governed by hormones, and the only reliable hack for now seems to be significantly lowering insulin by switching to ketogenic diet (or a variation thereof, /r/zerocarb, /r/keto, Atkins, Dukan). I'd recommend this book https://en.wikipedia.org/wiki/Good_Calories,_Bad_Calories with understanding that a lot of nutrition and diet science is in very premature stage because of World War 2 and lack of funding thereafter.
I once read that different kinds of food deliver calories in forms with different degrees of absorb-ability.
Source: http://www.iflscience.com/health-and-medicine/why-most-food-...