Gain-of-function research is defined as "research that improves the ability of a pathogen to cause disease." Meanwhile, directed evolution is defined as "the laboratory process by which biological entities with desired traits are created through iterative rounds of genetic diversification and library screening or selection."
God this is so dumb, these two definitions are not mutually exclusive: You use directed evolution as a method to do gain of function.
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God this is so dumb, these two definitions are not mutually exclusive: You use directed evolution as a method to do gain of function.